Rapidity bin multiplicity correlations from a multi-phase transport model

The central-arbitrary bin and forward-backward bin multiplicity correlation patterns for Au+Au collisions at $\sqrt{s_{NN}}$= $7.7-62.4$ GeV are investigated within a multi-phase transport (AMPT) model. An interesting observation is that for $\sqrt{s_{NN}} <19.6$ GeV Au+Au collisions, these two correlation patterns both have an increase with the pseudorapidity gap, while for $\sqrt{s_{NN}} >19.6$ GeV Au+Au collisions, they decrease. We mainly discuss the influence of different evolution stages of collision system on the central-arbitrary bin correlations, such as the initial conditions, partonic scatterings, hadronization scheme and hadronic scatterings. Our results show that the central-arbitrary bin multiplicity correlations have different responses to partonic phase and hadronic phase, which can be suggested as a good probe to explore the dynamical evolution mechanism of the hot dense matter in high-energy heavy-ion collisions.Comment: 7pages, 6 figures, accepted for publication in EPJ

Fermionic phase transition induced by the effective impurity in holography

We investigate the holographic fermionic phase transition induced by the effective impurity in holography, which is introduced by massless scalar fields in Einstein-Maxwell-massless scalar gravity. We obtain a phase diagram in $(\alpha, T)$ plane separating the Fermi liquid phase and the non-Fermi liquid phase.Comment: 17 pages, 9 figure

Improve Production Process Performance By Using Lean Management －A Case Study of Lady Underwear

People around the world work every year to improve the requirement standards of various commodities. Product life cycles are getting shorter, replaced by a number of innovative products; thus, in order to adapt to social changes, companies must develop a number of innovative products to attract consumers to buy. In Taiwan, most development occurs in small and medium traditional industries. Women’s underwear is a personal privacy product. As women are gradually being taken more seriously, women’s underwear products are gradually increasing in value, but the women’s underwear and underwear fabric design process is quite complex and time-consuming. To help enterprises improve production performance, this study introduces lean enterprise management, using IE tools for program analysis, which provides time to study the law, and 7S management practices, identifies problems, and proposes ways to improve in order to verify the practices and analysis of results. Research pointed out that introducing lean management for enterprises to improve process performance, so that women’s underwear product processes achieve significant improvement, improved results as follows: Before and after the improvement, GAP reached 23.83%; product production time was reduced; employee take line operation time reduced; quantization benefits of $1,909,425 improved the efficiency to$1,023,225, putting the cost at $106,200; and table bad rate increased the cost by$780,000. These results show that in the present study, lean management practices successfully improved the production performance of the women’s underwear industry included in this study. It is expected that the process improvements can provide a method for the lingerie industry to continuously improve and succeed in raising the performance feedback of employees to increase cohesion so that the company reaps more profits and benefits

Trace initial interaction from final state observable in relativistic heavy ion collisions

In order to trace the initial interaction in ultra-relativistic heavy ion collision in all azimuthal directions, two azimuthal multiplicity-correlation patterns -- neighboring and fixed-to-arbitrary angular-bin correlation patterns -- are suggested. From the simulation of Au + Au collisions at 200 GeV by using the Monte Carlo models RQMD with hadron re-scattering and AMPT with and without string melting, we observe that the correlation patterns change gradually from out-of-plane preferential one to in-plane preferential one when the centrality of collision shifts from central to peripheral, meanwhile the anisotropic collective flow v_2 keeps positive in all cases. This regularity is found to be model and collision energy independent. The physics behind the two opposite trends of correlation patterns, in particular, the presence of out-of-plane correlation patterns at RHIC energy, are discussed.Comment: 5pages, 4figure

A chalcone derivative reactivates latent HIV-1 transcription through activating P-TEFb and promoting Tat-SEC interaction on viral promoter.

The principal barrier to the eradication of HIV/AIDS is the existence of latent viral reservoirs. One strategy to overcome this barrier is to use latency-reversing agents (LRAs) to reactivate the latent proviruses, which can then be eliminated by effective anti-retroviral therapy. Although a number of LRAs have been found to reactivate latent HIV, they have not been used clinically due to high toxicity and poor efficacy. In this study, we report the identification of a chalcone analogue called Amt-87 that can significantly reactivate the transcription of latent HIV provirses and act synergistically with known LRAs such as prostratin and JQ1 to reverse latency. Amt-87 works by activating the human transcriptional elongation factor P-TEFb, a CDK9-cyclin T1 heterodimer that is part of the super elongation complex (SEC) used by the viral encoded Tat protein to activate HIV transcription. Amt-87 does so by promoting the phosphorylation of CDK9 at the T-loop, liberating P-TEFb from the inactive 7SK snRNP, and inducing the formation of the Tat-SEC complex at the viral promoter. Together, our data reveal chalcones as a promising category of compounds that should be further explored to identify effective LRAs for targeted reversal of HIV latency

Existence of solutions for a class of quasilinear degenerate p(x)p(x)-Laplace equations

We study the existence of weak solutions for a degenerate p(x)-Laplace equation. The main tool used is the variational method, more precisely, the Mountain Pass Theorem